| ◼ Treasury Secretary Scott Bessent announced new sanctions on Iran. In addition to existing energy sanctions, the U.S. will now target technology, shipping, and other sectors. The Trump administration is also threatening to impose secondary sanctions on nations that continue doing business with Iran. The level of economic pain that Trump is seeking to inflict on Iran is more intense than anything the regime has faced before. And reports from inside Iran suggest that the economy is already faltering and experiencing runaway inflation. But Iran’s leaders have proven resilient through decades of sanctions and conflict with the U.S. and Israel. Iran might also escalate in retaliation, such as by increasing its attacks on the Gulf states. Ultimately, it will take months or even years of sustained effort for any strategy of economic warfare to be effective. Trump, whose patience with this conflict has been somewhat surprising to this point, will need to dig in for the long haul.
◼ The winning combination of the free market and human ingenuity appears to be yielding yet more remarkable medical advances. The Food and Drug Administration has just approved a drug, daraxonrasib, developed by Revolution Medicines, a small California company. The drug works by attacking a mutated cellular protein called KRAS, which fuels pancreatic and some other cancers that were previously thought to be untouchable. No longer. Daraxonrasib is not a cure, but it is a start. Compared with chemotherapy, daraxonrasib has been shown in trials to increase life expectancy by an additional six months, and sometimes much longer. Former Senator Ben Sasse is currently taking the drug, and we are delighted to hear that he is benefiting from it. Meanwhile, Moderna and Merck have announced promising results from a late-stage trial of an mRNA-based “personalized” cancer vaccine against melanoma. A personalized vaccine takes aim at a specific cellular mutation, meaning that treatment will involve less collateral damage and appears to limit both the spread and recurrence of the disease. We stand alongside medical research, yelling Onward.
◼ Americans are increasingly alarmed by the proliferation of Flock cameras, a brand of AI-powered automated license-plate readers that record passing cars. Critics fear that the cameras might enable mass surveillance. When used properly, however, they have proven to be an effective law enforcement tool for flagging vehicles linked to active investigations. Flock cameras help the police arrest countless suspects and locate thousands of missing persons. But there have also been several cases of misuse by officers, who have used Flock’s database to track civilians for personal reasons. To earn back the trust of their communities, local governments must balance the technology’s genuine public safety benefits with firm guardrails.
◼ The murder trial of Lindsay Clancy has inspired a ghoulish public response. In 2023, Clancy, a 36-year-old mother, allegedly strangled her three young children to death in her basement after sending her husband on an errand. She then attempted to commit suicide by leaping from a second-story window but only paralyzed herself. Outside the courthouse, protesters have assembled to defend Clancy, claiming that she is an innocent victim. On social media, meanwhile, Clancy has gained a passionate following of sympathizers who seek to justify or excuse her actions. Clancy had been prescribed a range of medications to treat psychological problems including depression, insomnia, and suicidal ideation. According to her defense team, the drugs induced psychosis, which drove her to the killings. The struggles often experienced by new mothers should, of course, be taken seriously. But there is ample evidence to suggest that Clancy carefully planned the murders, sending her husband away and calculating how long he would be out of the house. Mental distress cannot excuse such a ghastly crime.
◼ Tim Curry was an impossibly charming character actor. A stage player at heart, he first found fame portraying Dr. Frank-N-Furter in the then wildly transgressive theater-to-film adaptation of The Rocky Horror Picture Show. Curry demonstrated his versatility in countless supporting roles on film and leading ones on stage. He used his natural expressiveness to play characters as diverse as the cannier-than-he-seems butler in Clue, the devil himself in Ridley Scott’s Legend, Long John Silver in Muppet Treasure Island, and even a man dismembered by superintelligent apes in Congo. Always invested in the role and the lovely absurdity of the show. Dead at 80. R.I.P.
◼ Dolly Parton was the queen of country music. During her six-decade career as a singer and songwriter, she was inducted into the Country Music Hall of Fame, the Songwriters Hall of Fame, and the Rock and Roll Hall of Fame. She wrote more than 3,000 songs, 25 of which reached No. 1 on the Billboard country charts. In the 1980s, she turned to Hollywood, landing starring roles in 9 to 5, The Best Little Whorehouse in Texas, and Steel Magnolias. A prolific philanthropist, her book-gifting program, Dolly’s Imagination Library, has provided more than 300 million books to children around the world. She also donated millions of dollars over the years to medical research and disaster relief. Her sweet twang, blonde wigs, and altruistic heart will be deeply missed. We will always love you, Dolly. Dead at 80. R.I.P. |